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Premature rupture of membranes, particularly when preterm, places the pregnancy at risk, but can be confused with urine leakage. Alere Actim® PROM detects IGFBP-1, a specific marker of amniotic fluid in a vaginal sample. The test is used to help diagnose the rupture of fetal membranes in pregnant women.
Only one-fifth of women presenting with suspected pre-term labor will deliver preterm, leading to many women being subjected to unnecessary interventions. Alere Actim® Partus detects the presence of phIGFBP-1, a marker of the fetal membranes detaching from the decidua, appearing in cervical secretions when delivery is approaching. The test helps predict the risk of preterm or imminent delivery.